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Diagnosis: Minimal Change Disease in Remission
Follow-up tests performed the same week as the biopsy (one month after the start of treatment) showed that the proteinuria had disappeared, as well as the hematuria and increased blood pressure: everything was normal. These findings correlate with the normal ultrastructural appearance of the podocytes, indicating remission of the nephrotic syndrome..
See the chapter: Minimal Change Disease of our Tutorial.
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References
- Teh YM, Lim SK, Jusoh N, Osman K, Mualif SA. CD80 Insights as Therapeutic Target in the Current and Future Treatment Options of Frequent-Relapse Minimal Change Disease. Biomed Res Int. 2021:6671552. [PubMed link]
- Rovin BH, Caster DJ, Cattran DC, Gibson KL, Hogan JJ, Moeller MJ, Roccatello D, Cheung M, Wheeler DC, Winkelmayer WC, Floege J; Conference Participants. Management and treatment of glomerular diseases (part 2): conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2019;95(2):281-295. [PubMed link]
- Mansur A. Minimal change Disease. In Medscape [Visit page (link)]:
- Bertelli R, Bonanni A, Caridi G, Canepa A, Ghiggeri GM. Molecular and Cellular Mechanisms for Proteinuria in Minimal Change Disease. Front Med (Lausanne). 2018;5:170. [PubMed link].