Case
106 With discussion |
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Versión
en Español |
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CASE 106 (December 2014)
Clinical information
A five month-old girl presented with symptoms of malnutrition and severe urinary tract infection, with signs of sepsis and acute renal failure: serum creatinine 1.4 mg/dL. Both blood and urine cultures were positive for Escherichia coli, and antibiotic therapy was started. Severe, almost symmetrical, bilateral nephromegaly was evident on computed tomography (Figures 1 and 2). Voiding cystourethrography showed no urinary tract abnormalities.
Bilateral renal biopsies were performed.See the images.
Figure 1.
Figure 2.
Figure 3. H&E, X400.
Figure 4. H&E, X400.
Figure 5. H&E, X400.
Figure 6. H&E, X400.
Figure 7. PAS, X400.
Figure 8. PAS, X400.
What is your diagnosis?