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Case 147
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Diagnosis: Subepithelial pelvic hematoma of the kidney (Antopol-Goldman Lesion)

Subepithelial renal pelvic hematoma was firstly described by Antopol, and Goldman. (Antopol W, Goldman L Urol Cutaneous Rev. 1948; 52:189-95.[PubMed link]) All of this patients (7 cases) had undergone nephrectomy with the initial diagnosis of kidney or pelvic tumour.

Its etiology is not known precisely. In the literature, various conditions have been associated with its etiology in miscellaneous case series, which include trauma, congenital malformations (bifid pelvis, fetal lobulation, aberrant vessels, and ureteral insertion abnormalities), hypertension, excessive analgesic use, and anticoagulant therapy. In the literature there are cases from neonatal age group, but it is more frequently observed in individuals older than 40 years without any predilection for male or female gender. Majority of the patients had hematuria and filling defect in the renal pelvis and undergone nephroureterectomy, and diagnosis could only be made after histopathological analyses, Cases diagnosed using only cross-sectional imaging methods, and followed up conservatively have been reported. (Altay B, et al. Subepithelial pelvic hematoma of the kidney (Antopol-Goldman Lesion). Turk J Urol. 2015;41(1):48-50. [PubMed link]).

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References

  • Altay B, Barışık CC, Erkurt B, Kiremit MC. Subepithelial pelvic hematoma of the kidney (Antopol-Goldman Lesion). Turk J Urol. 2015;41(1):48-50. [PubMed link] [Free Full Text]
  • Sánchez Zalabardo D, De Pablo Cárdenas A, Fuertes Zárate A, Miranda Orella L, Cuesta Alcalá JA, Millán Serrano JA. Antopol-Goldman lesion: a rare clinical entity in the differential diagnosis of macroscopic hematuria. Arch Esp Urol. 2012;65(2):258-62. [PubMed link]
  • Chan IH, Lam WW, Wong KK, Tam PK. Renal pelvis haematoma causing pelviureteric obstruction: a first case of Antopol-Goldman lesion in a neonate. J Paediatr Child Health. 2010;46(6):361-2. [PubMed link]
  • Eccher A, Brunelli M, Gobbo S, Ghimenton C, Grosso G, Iannucci A, Dalla Palma P, Menestrina F, Martignoni G. Subepithelial pelvic hematoma (Antopol--Goldman lesion) simulating renal neoplasm: report of a case and review of the literature. Int J Surg Pathol. 2009;17(3):264-7. [PubMed link]

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