Case
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Diagnosis: Postinfectious Glomerulonephritis
Very beautiful the humps, evidenced with the trichrome stain.
The patient had impetigo 3 weeks before onset of symptoms. Two months after the biopsy, she is well, no alteration of renal function and urinalysis normal.
See the chapter Proliferative Endocapillary Glomerulonephritis of our tutorial.
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References
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Nasr SH, Radhakrishnan J, D'Agati VD. Bacterial infection-related glomerulonephritis in adults. Kidney Int. 2013 Jan 9. [Epub ahead of print] [PubMed link]
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Sethi S, Fervenza FC, Zhang Y, Zand L, Meyer NC, Borsa N, Nasr SH, Smith RJ. Atypical postinfectious glomerulonephritis is associated with abnormalities in the alternative pathway of complement. Kidney Int. 2012 Dec 12. [Epub ahead of print] [PubMed link]
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Mandache E, Penescu MN. The association of polymorphonuclears with humps in acute postinfectious glomerulonephritis. Rom J Morphol Embryol. 2012;53(3):629-33. [PubMed link]
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Kambham N. Postinfectious glomerulonephritis. Adv Anat Pathol. 2012 Sep;19(5):338-47. [PubMed link]
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Nast CC. Infection-related glomerulonephritis: changing demographics and outcomes. Adv Chronic Kidney Dis. 2012;19(2):68-75. [PubMed link]
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Nadasdy T, Hebert LA. Infection-related glomerulonephritis: understanding mechanisms. Semin Nephrol. 2011;31(4):369-75. [PubMed link]