CASE 84 (February 2013)
A 46-year-old woman with a history of grade 1 hypertension, about 10 years of evolution, suffered head trauma and brain death. Renal function and urine analysis were normal.
After the family's consent, both kidneys were obtained for transplantation.
A donor renal biopsy was performed. See the images of the renal biopsy.
Figure 1. H&E, X100.
Figure 2. H&E, X100.
Figure 3. H&E, X200.
Figure 4. H&E, X200.
Figure 5. Global glomerulosclerosis: 5 of 145. Masson's trichrome stain, X400.
Figure 6. Hyalinization of afferent and efferent arterioles. PAS, X400.
Figure 7. Methenamine-silver stain, X400.
Figure 8. Three glomeruli with nodules. Methenamine-silver stain, X400.
Figure 9. Masson's trichrome stain, X400.
Figure 9. PAS, X400.
Total global glomerulosclerosis: 3.4%; interstitial fibrosis and tubular atrophy: <5%.
What is your diagnosis?
Would you transplant these kidneys?