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CASE 154 (December 2018)

Clinical information

The patient is a 6-year-old girl with persistent microscopic hematuria and episodic gross hematuria, 2 years of evolution; 4 episodes of macrohematuria in the last year. Proteinuria: 230 mg/24h. Serum creatinine: 0.4 mg/dL. Negative autoimmunity studies. AELOs in normal values. Normal serum complement. Studies for viruses: negative. She does not have high blood pressure. No pathological personal history.

See the images of the renal biopsy.

Figure 1. Methenamine-silver, &E, X100.

Figure 2. H&E, X200.

Figure 3. H&E, X400.

Figure 4. H&E, X400.

Figure 5. Methenamine-silver, X400.

Figure 6. Masson's trichrome stain, X400.

Figure 7. EM, original magnification X2,100.

Figure 8. EM, original magnification X2,100.

Figure 9. EM, original magnification X2,100.

Direct immunofluorescence for IgA, IgG, IgM, C3, and C1q: Negative.

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