Nephropathology
   
Case 96
Diagnosis
 
     
Versión en Español

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Diagnosis: Post-transplant lymphoproliferative disorden: Diffuse large B-cell lymphoma with plasma cell differentiation, related to Epstein-Barr virus

Infiltrating lymphocytes could suggest rejection, however the mass evidenced on ultrasound and the atypical appearance of some lymphocytes led us to ask the opinion of a hematopathologist, who with the help of immunohistochemistry and in situ hybridization did diagnosis.

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References

  • Juan RS, Commoli P, Caillard S, Moulin B, Hirsch H, Meylan P. EBV-related Post Transplant Lymphoproliferative Disorder (PTLD) in solid organ transplant (SOT) recipients. Clin Microbiol Infect. 2014 Jan 29. [PubMed link]
  • Karuturi M, Shah N, Frank D, Fasan O, Reshef R, Ahya VN, Bromberg M, Faust T, Goral S, Schuster SJ, Stadtmauer EA, Tsai DE. Plasmacytic post-transplant lymphoproliferative disorder: a case series of nine patients. Transpl Int. 2013;26(6):616-22. [PubMed link]
  • Murukesan V, Mukherjee S. Managing post-transplant lymphoproliferative disorders in solid-organ transplant recipients: a review of immunosuppressant regimens. Drugs. 2012;72(12):1631-43. [PubMed link]
  • Jagadeesh D, Woda BA, Draper J, Evens AM. Post transplant lymphoproliferative disorders: risk, classification, and therapeutic recommendations. Curr Treat Options Oncol. 2012;13(1):122-36. [PubMed link]

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