CASE 47 (January 2010)

Clinical information

A 56-year-old woman died due to septic shock; the infection was originated in her lungs.

At autopsy we found prominent renal alterations.

There is in the following histologic images of her kidneys a pathognomonic lesion. What is the disease and what is the pathognomonic lesion?

Figure 1. H&E, X400.

Figure 2. Masson's trichrome stain, X400.

Figure 3. Masson's trichrome stain, X400.

Figure 4. Masson's trichrome stain, X400.

Figure 5. Methenamine-silver, X400.

Figure 6. Methenamine-silver, X400.

Figure 7. PAS, X400.

Figure 8. Masson's trichrome stain, X400.

Figure 9. PAS, X400.

What is the pathognomonic change?

And, what is the disease?

See diagnosis and discussion

[Top]