CASE 212 (October 2023)

Clinical information

A 36-year-old man with end-stage chronic kidney disease of unknown cause is transplanted from a cadaveric donor. In the immediate post-transplant period there was good diuresis, with a progressive decrease in creatinine until the 4th day: 1.7 mg/dL, then it remained stationary and on the 7th day it rose to 2.9 mg/dL, therefore, a kidney biopsy was performed. The patient is asymptomatic and continues to have good diuresis. Normal hemoleukogram, platelets 234,000/mm2.

Look at the images.

Figure 1. H&E, X100.

Figure 2. H&E, X200.

Figure 3. H&E, X400.

Figure 4. H&E, X400.

Figure 5. H&E, X400.

Figure 6. H&E, X200.

Figure 7. H&E, X400.

Figure 8. PAS, X400.

Figure 9. Methenamine-silver stain, X400.

Figure 10. Masson's trichrome stain, X400.

Figure 11. Immunostaining for C4d: positivity in 100% of peritubular capillaries, X400.

What is your diagnosis?

See diagnosis and discussion

[Top]